A large-scale Danish study from 2011 found that xanthelasma is a warning sign of an increased risk of heart disease. The results showed that participants with xanthelasma were more prone to heart attacks or other heart diseases, regardless of other known risk factors such as obesity, smoking, or high blood pressure. Xanthelasma also increased the risk of heart attacks even among study participants without lipid metabolism disorders. The website advises people with xanthelasma to undergo heart examinations to detect and treat any potential diseases in a timely manner. It also recommends working to eliminate these cholesterol deposits by following a healthy diet, engaging in regular physical activity, and using cholesterol-lowering medication. The German pharmacists' official portal, Apotheke.de, states that xanthelasma are small, yellowish spots or bumps that appear around the eyes due to cholesterol buildup in the eyelid tissue.
